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Albumin in the blood

What is the albumin?

Albumin is a high concentration contained in the blood protein fraction, the total percentage which is up to 65% of the total plasma. The liver is the synthesis. Directly molecule includes a huge amount of amino acids, there are up to 600, but it belongs to the group of low molecular weight simple proteins. If 40% of all protein fractions is in the blood, then the rest of the stock distributed in the lymph, you can find it in the cerebrospinal fluid, and interstitial fluid.

Albumins not just circulate in the bloodstream, they will perform a number of vital functions, namely:

  • Direct the maintenance of osmotic pressure of blood plasma occurs due to the protein. With this capability, a person with a normal level of albumin in the blood, fluid from the blood stream and the swelling in the body do not appear. It is worth noting that these microscopic fractions and its constituent amino acids maintain the pressure in the plasma by 80%. Naturally, with any kidney disease, they quickly come out with the urine, which is why almost all of the kidney disease are accompanied by swelling.
  • These components of blood perform the backup function. They store reserves of amino acids for the human body. During prolonged fasting, they will be spent in the first place.
  • Performing transport functions are also included in the tasks of albumin, carries it in the blood various substances, especially those that are poorly soluble in water. Free fatty acids are "passengers"of the protein, and, steroids, vitamins (fat soluble) and in addition some ions. Protein involved in the transport by the bloodstream many drugs, particularly penicillin, warfarin, and aspirin. Also fraction of the protein carries a number of hormones and connects non-polar substances, such as cholesterol, fatty acids and bilirubin. Due to the fact that the protein is unpretentious in the choice of their"passengers"for transport and carries a huge number of different substances, the doctors called it the"molecule of the taxi."

Its name is a kind of "storage of amino acids" derived from Latin albus which means white, it is a protein in pure form and does not contain a single gram of carbohydrates. In addition to the human body it is quite common in nature, so it can be found in chicken eggs and in some plants. Depending on the amount of blood containsalbumin can be judged and how a healthy human body.


Rate of blood in women and men

As for the rule of albumin in the blood and sex of the person, here there is no significant difference. The big role is played directly by the age of the Respondent, who had taken the fence on the study. That is why, speaking about the norm in the blood of men and women, it is more logical to use age-dividing circuit. So, if you count its value in grams per liter of fluid, then the children till 14 years it is normal from 38 to 54 units. As for adults, the normal change is insignificant and at the age of 14 to 60 years, the figure ranges from 35 to 50. Crossing the threshold of 60 years, Norma of albumin in the blood is somewhat reduced and amounts to from 34 to 38.

If the protein increases or decreases, it may be due to both qualitative and quantitative changes. But since the first is quite rare, due to the fact that the composition of the homogeneous albumin, the more common quantitative changes, which appear Hypo - and hyperalbuminemia. They can be caused by both external and internal factors indicate a pathology in the body.


Albumin in my blood

Quite often the reason for the increase in albumin in the blood is an obvious dehydration. But it is not always the lack of water is the deviation from the norm.

Hyperalbuminemia quite rare, but frequently observed the following pathological processes in the human body:

Reduced albumin in the blood

Lowering the protein in the blood can also be caused by a number of diseases.

If any indicators are available, then that makes the doctor suspect some pathology of the body, namely:

  • Diseases associated with dysfunction of the liver, e.g. cirrhosis, atrophy, hepatitis, or carcinoma.

  • Fasting to reduce body mass, as well as other errors in the diet. This is especially true of low-protein diets, and not balanced amino acid composition of the dietary pattern. Naturally, such conditions occur in malnutrition and anorexia. Cachexia can cause decrease in albumin in the blood.
  • Pathology of gastrointestinal tract of various origins.
  • Losses associated with burns injuries tissues.
  • Nephrotic syndrome, diabetic nephropathy, as kidney disease. Especially the loss of relevant in chronic nature of the disease.
  • After bleeding, especially profuse, and the introduction of blood substitutes, in a natural way reduced the level of albumin.
  • Different kinds of fevers, blood poisoning, postponed or current infectious diseases, tumors, wearing a malignant character, rheumatic diseases, in short, all those States, causing increased catabolism.

  • If you increase blood volume, namely gipergidratace.
  • Heart failure, wearing stagnant.
  • A hereditary disease.
  • In newborns because their liver cells are not yet fully Mature.

As for conditions not caused by a specific disease, to include pregnancy. A woman's body just "shares" with the fetus's own albumin. A similar condition may also occur during lactation. To help in this situation may a balanced diet.

Often, the reduction of albumin, and in a fairly significant concentration can be observed among fans of cigarettes. So, in the blood of heavy smokers the protein will be reduced by far. The same applies to the abuse of spirituous drinks.

Welcomecertain drugs, especially in overdose of medicines, leading to decreased albumin in the blood, so their reception should be under medical supervision. In particular, it relates to esotropia, ibuprofenbuy group, phenytoin and others.

Regarding the study of the level of albumin, the blood sampling should be conducted strictly on an empty stomach in a calm state. Since the sample can affect even the excessive exercise or prolonged exposure of the subject in an upright position.

The impressive decrease level of albumin, below the level of 22 g/l may occur this life-threatening condition like pulmonary edema.