Scleroderma

Causes of scleroderma

The causes contributing to the development of scleroderma, include stress, hypothermia, severe or chronic infectious diseases, radiation, chemicals.

An important role in the development of the disease plays a dysfunction of fibroblasts and other cells that produce collagen. What matters is the reaction of the autoimmune system on the skin. Supposedly different disorders of the endocrine system, metabolism and other, together with the negative impact of external factors, create favorable conditions for the development of pathologies in the system of connective tissue such as skin and blood vessels, and digestive organs, liver, lungs, etc.

The symptoms of scleroderma

The focal form appears in small rounded lesions. During the development of scleroderma, they pass through three stages: first spots appear, then they turn into plaques, occur atrophy. At the beginning of scleroderma is weak: there is one or a few spots of lilac-pink, rounded or oval. Further, in the center of the spot formed by the seal, which with the course of the disease turns into a dense plaque with a smooth brilliant surface white or yellowish.

Types of scleroderma

The most common types and more studied consider systemic and limited scleroderma.

Systemic scleroderma affects many organs and tissues.

There is a kind of systemic sclerosis, called diffuse. This rare form occurs only five percent of patients. This form is dangerous because negative changes occur in the internal organs, so the outcome her sad.

Limited scleroderma is usually reflected on the skin and adjacent layers, although other parts of the body are harmed by it.

Patchy sclerosis is one of the types of localized scleroderma. Formed a certain amount of spots. Very often, spots appear exactly where there was damaged skin. Very rarely, but it happens that this scleroderma goes away.

Linear scleroderma usually affects kids. The localization of the disease – the forehead, over the disease it is moving in the direction of the hair. In the casethe manifestation of scleroderma on feet, you may experience venous ulcers. It happens that in a family this disease affects a few people. Rare annular form of the disease.

Generalized form of scleroderma affects large areas of the body. Very common in children, although adults from this disease is not insured too.

The disease of white spots normally happens to women. Children are affected very rarely.

Subcutaneous, morphea the skin becomes thick and rough. Upon delivery of blood picture changes.