Glandular hyperplasia of the endometrium

Causes and symptoms of glandular hyperplasia of endometrium

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What is glandular endometrial hyperplasia?

Endometrial hyperplasia is called pathology, in which the tissue growth of the uterine mucosa. The disease is associated with hormonal disorders, occurs when excessive production of estrogen and lack of progesterone. There are several types of endometrial hyperplasia. They differ in thickness of the endometrium.

Glandular endometrial hyperplasia occurs when the growing glandular tissue. This occurs when the extension gap between the glands of the mucous membrane of the uterus. While the glandular tissue has a homogeneous structure, and the thickness of the endometrium with the variety of the disease does not exceed one and a half inches.

Causes and types of glandular hyperplasia of endometrium

The main causes glandular endometrial hyperplasia are factors such as menopause, presence of follicular cysts, obesity, and anovulation. Risk are also tumors of the granulosa cells, hyperglycemia and syndrome of persistence of the follicle.

Late diagnosis and lack of treatment of this disease pose a risk of endometrial cancer. At risk are mostly women in postmenopause and women with atypical hyperplasia adamantanol. It diffuse and focal forms are precancerous.

Other forms of endometrial hyperplasia are glandular-cystic hyperplasia, cystic dilated glands and intensive expansion of the glandular epithelium.

Symptoms of glandular hyperplasia of endometrium

Often glandular hyperplasia of the endometrium occurs without obvious clinical symptoms. But common manifestation is considered dysfunctional uterine bleeding that occur after the menstrual cycle (delayed menstruation). Such bleeding can be prolonged and profuse, and the blood loss can be moderate and abundant. As a consequence, developed anemic symptoms: weakness, fatigue, loss of appetite.

Between periods can be observed bloody discharge from the vagina. Often in connection with anovulation in women can sometimes be infertility. By the way, that infertility is reason for a trip to the doctor, who will diagnose this pathology. Among the symptoms are also marked pain in the lower partbelly.

Diagnose glandular hyperplasia of the endometrium possible with a diagnostic curettage performed immediately before menstruation. In the diagnosis actively used as hysteroscopy and ultrasonography.

Treatment of glandular hyperplasia of endometrium

Treatment of glandular hyperplasia of the endometrium is chosen individually, depending on the type of disease, the causes of its development and the patient's age. Young girls are shown hormonal therapy, which consists in cyclic administration of estrogen with a progestin. The course of treatment is usually six months, followed by re-scraping of the endometrium.

If such treatment fails and ovulation does not come, estrogens and progestins are recommended to be taken orally. In the case of urgent need to induce ovulation do it with klomifentsitrat.

Women during menopause is most often recommended therapy with cyclic receiving depo-Provins and medroxyprogesterone acetate. The course of treatment usually lasts from three to six months, after which repeat the biopsy.